Thursday, February 27, 2014

Field Virology 6th available

Fields Virology is the authoritative reference book for virology, providing definitive coverage of all aspects of virology, including thorough coverage of virus biology as well as replication and medical aspects of specific virus families.  With the regular outbreaks of influenza, noroviruses as well as other emerging and re-emerging viruses it is essential to have the most up-to-date information available.
With this Sixth Edition, all chapters have been completely updated, an important new emphasis has been placed on virus discovery and emerging viruses. Viruses associated with cancer, including the new human polyomaviruses, are highlighted in this Sixth Edition and new chapters have been added on circoviruses and mimiviruses. 
While the main focus of this edition continues to be on viruses, information on prions and the infectious spongiform encephalopathies are also included.


FEATURES• 2-volume set
• Full color throughout with over 1,000 illustrations in total and most chapters provide key figures for use as lecture slides
• Online companion website with fully searchable text, all references linked to PubMed and additional material not found in the print for access to content anytime
• New coverage of emerging and viruses, including those causing influenza and HIV
• Updated coverage of viruses and cancer
• Coverage includes virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, virus evolution and immunization
• Thorough coverage of all viruses of medical importance, including both basic science and clinical features
• New chapters on circoviruses and mimiviruses and a new section on Chikungunya virus have been added
• Important advances in antivirals, including new HCV protease inhibitors and HIV integrate inhibitors

http://www.lww.com/webapp/wcs/stores/servlet/product_Fields-Virology_11851_-1_9012053_Prod-9781451105636?cm_sp=PE-MED-InfectiousDiseases-_-Banner-InfectiousDiseases-_-Left-NoPromo-FieldsVirology-NewEdition

Wednesday, February 26, 2014

plant factory-producing medicine

制造蛾信息素的植物工厂
蛾类通过信息素的交流来寻找配偶,人工合成的信息素通常用来监控或者干扰害虫的信息素交流。该研究以本生烟作为工厂通过瞬时表达最多四个编码基因来连续合成途径,我们生产出两种蛾类特异的多组分性信息素。来自经过遗传修饰植物的脂肪醇片段加速了属于小巢蛾Yponomeuta evonymellaY. padella性信息素的模拟过程。这些混合物非常有效和特异的诱捕雄性蛾,这说明符合常规的性信息素。我们的长期目标是在遗传修饰的植物中设计量身定做的任何蛾类信息素。这种半合成制备性信息素是一个生产中等至大规模生产高质量低污染的非常新颖和非常划算的方式



Moths depend on pheromone communication for mate finding and synthetic pheromones are used for monitoring or disruption of pheromone communication in pest insects. Here we produce moth sex pheromone, using Nicotiana benthamiana as a plant factory, by transient expression of up to four genes coding for consecutive biosynthetic steps. We specifically produce multicomponent sex pheromones for two species. The fatty alcohol fractions from the genetically modified plants are acetylated to mimic the respective sex pheromones of the small ermine moths Yponomeuta evonymella and Y. padella. These mixtures are very efficient and specific for trapping of male moths, matching the activity of conventionally produced pheromones. Our long-term vision is to design tailor-made production of any moth pheromone component in genetically modified plants. Such semisynthetic preparation of sex pheromones is a novel and cost-effective way of producing moderate to large quantities of pheromones with high purity and a minimum of hazardous waste.

http://www.nature.com/ncomms/2014/140225/ncomms4353/full/ncomms4353.html

Sunday, February 23, 2014

Fish skeleton

Novelli meal,
After 10 minutes 

Friday, February 21, 2014

Fifth edition Plant Virology

The seminal text Plant Virology is now in its fifth edition. It has been 10 years since the publication of the fourth edition, during which there has been an explosion of conceptual and factual advances. 

The fifth edition of Plant Virology updates and revises many details of the previous edition while retaining the important earlier results that constitute the field's conceptual foundation. Revamped art, along with fully updated references and increased focus on molecular biology, transgenic resistance, aphid transmission, and new, cutting-edge topics, bring the volume up to date and maintain its value as an essential reference for researchers and students in the field.


  • Thumbnail sketches of each genera and family groups
  • Genome maps of all genera for which they are known
  • Genetic engineered resistance strategies for virus disease control
  • Latest understanding of virus interactions with plants, including gene silencing
  • Interactions between viruses and insect, fungal, and nematode vectors
  • Contains over 300 full-color illustration

Address:

http://www.sciencedirect.com/science/book/9780123848710